Estée Lauder Companies has made a minority investment in luxury clinical skincare brand 111SKIN. Terms of the investment were not disclosed.

111SKIN was founded in 2012 by plastic and reconstructive surgeon Dr. Yannis Alexandrides to accelerate his patients' healing time following procedures. 

111SKIN distributes through luxury retail, e-commerce and high-end spa channels including Harrods, Bluemercury, Nordstrom, Mandarin Oriental, and Aman. It has a direct-to-consumer business representing approximately 20% of sales. The brand has a diversified global footprint, with North America representing approximately 40% of 2025 sales, and an established presence across China, the UK, Europe and Asia Pacific.

Yannis will remain actively involved in the brand and will continue to lead 111SKIN alongside its experienced management team.

For more information, visit elcompanies.com.